Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004921 | 0.89 | ALOX5AP (0.36) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL2008523 | 0.80 | CYP1A2 (0.38) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL3971742 | 0.72 | ESR2 (0.44) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL3756901 | 0.70 | ALOX5AP (0.41) | ALOX5APTDP1 | |
| SCHEMBL11054996 | 0.70 | CYP1A2 (0.55) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL3762657 | 0.70 | ALOX5AP (0.51) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9778228 | 0.69 | CYP1A2 (0.56) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL8008479 | 0.69 | CYP1A2 (0.56) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL8570092 | 0.69 | CYP1A2 (0.56) | CYP1A2ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL2004716 | 0.68 | FAAH (0.37) | CYP1A2ESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960483-B2 | Adamantane derivative, composition comprising the derivative, and optical and electronic member using the composition | IDEMITSU KOSAN CO., LTD. (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090062481-A1 | ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1985617-A1 | ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062481-A1 | ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION | APP, ADAM17, PSD | CYP1A2 339/4885ESR1 704/4885ESR2 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.