Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21424367 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTUSP2CYP3A4 | |
| SCHEMBL21128890 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTUSP2CYP3A4 | |
| SCHEMBL13282214 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTUSP2CYP3A4 | |
| SCHEMBL23098234 | 0.91 | TSHR (0.31) | ALDH1A1LMNATSHR | |
| SCHEMBL20049752 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL12555769 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL12555791 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL18426851 | 0.83 | ALOX15 (0.34) | ALDH1A1USP2HPGDTSHR | |
| SCHEMBL20049545 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTUSP2CYP3A4 | |
| SCHEMBL12555789 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180100001-A1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180100001-A1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | TIMCC, SPPL2B, SCTR | ALDH1A1 4639/4885LMNA 3970/4885MAPT 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.