Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20050013 | 0.86 | CDK8 (0.38) | GRIN2BCHRNA7GRIN1PRMT5WDR77 | |
| SCHEMBL25586426 | 0.83 | GRIN2B (0.45) | GRIN2BCHRNA7GRIN1 | |
| SCHEMBL20049978 | 0.82 | CHRNA7 (0.45) | GRIN2BCHRNA7GRIN1 | |
| SCHEMBL25588372 | 0.79 | CHRNA7 (0.40) | GRIN2BCHRNA7 | |
| SCHEMBL25583779 | 0.75 | CHRNA7 (0.49) | GRIN2BCHRNA7 | |
| SCHEMBL20050011 | 0.75 | USP2 (0.40) | CHRNA7PRMT5WDR77 | |
| SCHEMBL20050023 | 0.73 | NPC1 (0.33) | GRIN2BCHRNA7GRIN1PRMT5WDR77 | |
| SCHEMBL20050084 | 0.73 | MAP4K4 (0.48) | GRIN2BGRIN1 | |
| SCHEMBL20049954 | 0.72 | PDGFRB (0.41) | CHRNA7 | |
| SCHEMBL20050002 | 0.70 | GRIN2B (0.44) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067786-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-04-12 | — | — | WO | disclosed |