Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25583779 | 0.86 | CHRNA7 (0.49) | PDGFRBPDGFRAALDH1A1KDM4ENPC1 | |
| SCHEMBL20049815 | 0.85 | PSMB5 (0.47) | PDGFRBPDGFRAGRM5ALDH1A1KDM4E | |
| SCHEMBL20050011 | 0.85 | USP2 (0.40) | PDGFRBPDGFRANPC1LMNACYP2A6 | |
| SCHEMBL20049975 | 0.83 | GRIN1 (0.36) | PDGFRBPDGFRACYP2A6MAP4K4PSMB5 | |
| SCHEMBL23283131 | 0.82 | KIF11 (0.50) | ALDH1A1KDM4ELMNAMAP4K4HPGD | |
| SCHEMBL20881385 | 0.82 | NOS1 (0.44) | KDM4ECYP2A6CHRNA7CYP3A4MAPT | |
| SCHEMBL25586426 | 0.81 | GRIN2B (0.45) | LRRK2FLT1MAP4K4CHRNA7CYP2C19 | |
| SCHEMBL20049894 | 0.81 | MAP4K4 (0.45) | EGLN1MAP4K4KIT | |
| SCHEMBL17066358 | 0.80 | CYP2A6 (0.52) | PDGFRBPDGFRAALDH1A1KDM4ENPC1 | |
| SCHEMBL20049978 | 0.80 | CHRNA7 (0.45) | PDGFRBPDGFRACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067786-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-04-12 | — | — | WO | disclosed |