SCHEMBL7565259

SCHEMBL7565259

Cc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.73
CA2 P00918 12/20 0.73
CA9 Q16790 6/20 0.73
CA12 O43570 5/20 0.73
HTT P42858 1/20 0.71
CA6 P23280 2/20 0.67
CA5A P35218 2/20 0.67
CA7 P43166 2/20 0.67
CA3 P07451 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
ALDH1A1 P00352 3/20 0.65
MAPT P10636 3/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
GAA P10253 1/20 0.65
LMNA P02545 1/20 0.65
MAPK1 P28482 1/20 0.65
GFER P55789 1/20 0.65
MCL1 Q07820 1/20 0.65
TDP1 Q9NUW8 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2005010 0.90 CA12 (0.81) CA1CA2CA9CA12HTT
SCHEMBL2240008 0.85 CA1 (0.71) CA1CA2CA9CA12HTT
SCHEMBL1417537 0.85 CA1 (0.71) CA1CA2CA9CA12HTT
SCHEMBL9001311 0.85 CA12 (0.72) CA1CA2CA9CA12HTT
SCHEMBL11705580 0.85 MEN1 (0.86) CA1CA2CA9CA12HTT
P-Toluenesulfonamide SCHEMBL4335239 0.83 CA1 (0.62) CA1CA2CA9CA12HTT
SCHEMBL153131 0.83 CA1 (1.00) CA1CA2CA9CA12HTT
SCHEMBL27466837 0.83 CA1 (1.00) CA1CA2CA9CA12HTT
P-Toluenesulfonamide SCHEMBL7370 0.82 CA2 (1.00) CA1CA2CA9CA12CA6
P-Toluenesulfonamide SCHEMBL31527821 0.82 CA2 (1.00) CA1CA2CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964526-A Synthesis and application of (4-benzyl (p-toluenesulfonyl) amino) benzenesulfonamide compound 赣南医学院 2024-05-03 CN claimed
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
CN-118978462-A Preparation method of N-sulfinylated sulfonamide derivative 赣南医科大学 2024-11-19 CN disclosed
CN-117964526-A Synthesis and application of (4-benzyl (p-toluenesulfonyl) amino) benzenesulfonamide compound 赣南医学院 2024-05-03 CN disclosed
WO-2002078970-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed