Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20050150 | 0.81 | POLB (0.62) | MAPTALDH1A1GAAMAPK1POLB | |
| SCHEMBL24433912 | 0.80 | ALDH1A1 (0.52) | MAPTALDH1A1GAAMAPK1FFAR1 | |
| SCHEMBL20050078 | 0.73 | MAPT (0.34) | MAPTALDH1A1GAAMAPK1POLB | |
| SCHEMBL21759061 | 0.72 | POLB (0.61) | MAPTALDH1A1GAAMAPK1POLB | |
| SCHEMBL20050149 | 0.72 | AOC3 (0.59) | MEN1KMT2ATSHRCYP2D6CYP1A2 | |
| SCHEMBL21759173 | 0.72 | POLB (0.76) | MAPTALDH1A1GAAMAPK1POLB | |
| SCHEMBL13866493 | 0.69 | POLB (0.81) | MAPTALDH1A1GAAMAPK1POLB | |
| SCHEMBL6027881 | 0.69 | POLB (0.81) | MAPTALDH1A1GAAMAPK1POLB | |
| SCHEMBL3416662 | 0.69 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL11013442 | 0.69 | ALDH1A1 (0.51) | MAPTALDH1A1GAAMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067685-A1 | SMALL MOLECULE AMPK ACTIVATORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-04-12 | — | — | WO | disclosed |