Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759173 | 0.89 | POLB (0.76) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL13866493 | 0.86 | POLB (0.81) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL6027881 | 0.86 | POLB (0.81) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL21759059 | 0.85 | POLB (0.67) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL21759172 | 0.82 | POLB (0.71) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL5884965 | 0.82 | POLB (0.71) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL24433912 | 0.82 | ALDH1A1 (0.52) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL20050157 | 0.81 | MAPT (0.48) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL20050081 | 0.79 | ABCB1 (0.67) | POLBALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL21759061 | 0.78 | POLB (0.61) | POLBALDH1A1MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599048-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-08-13 | — | — | EP | claimed |
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| CN-119868551-A | New use of F-box protein 48 inhibitor and medicine for treating ischemic cerebrovascular disease | 四川大学华西医院 | 2025-04-25 | — | — | CN | claimed |
| CN-119654404-A | Methods and compositions for producing oligodendrocyte progenitor cells | 特雷尔赫德生物系统股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| EP-4444870-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2024-10-16 | — | — | EP | claimed |
| CN-118382694-A | Methods and compositions for generating human erythroid progenitors | 特雷尔赫德生物系统股份有限公司 | 2024-07-23 | — | — | CN | claimed |
| WO-2024063818-A9 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-05-23 | — | — | WO | claimed |
| US-20240117302-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-04-11 | — | — | US | claimed |
| WO-2024076758-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-04-11 | — | — | WO | claimed |
| WO-2024063818-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-03-28 | — | — | WO | claimed |
| US-20240043798-A1 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-02-08 | — | — | US | claimed |
| WO-2023107477-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2023-06-15 | — | — | WO | claimed |
| US-20230174938-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2023-06-08 | — | — | US | claimed |
| US-12610034-B2 | Real-time quality data marketplace | QCIFY INC (US) | 2026-04-21 | — | — | US | disclosed |
| US-20260029783-A1 | AUTOMATIC PRODUCT DETECTION AND MODEL SWITCHING | PEETERS RAF (US) | 2026-01-29 | — | — | US | disclosed |
| CN-120960188-A | Application of BC1618 in preparing central nervous system protecting medicine | 中国科学院动物研究所 | 2025-11-18 | — | — | CN | disclosed |
| US-11040935-B2 | Small molecule AMPK activators | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-06-22 | — | — | US | disclosed |
| WO-2021050538-A1 | METHODS AND MATERIALS FOR INCREASING LEVEL OF PHOSPHORYLATED AMPK PROTEIN | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20200062693-A1 | SMALL MOLECULE AMPK ACTIVATORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-02-27 | — | — | US | disclosed |
| WO-2018067685-A1 | SMALL MOLECULE AMPK ACTIVATORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040935-B2 | Small molecule AMPK activators | PRKAG1, PRKAG2, PRKAA1 | POLB 3111/4885ALDH1A1 2770/4885MAPT 2764/4885 |
| US-12610034-B2 | Real-time quality data marketplace | SET, HES1, TMCO1 | POLB 1075/4885ALDH1A1 4355/4885MAPT 4203/4885 |
| US-20200062693-A1 | SMALL MOLECULE AMPK ACTIVATORS | PRKAG1, PRKAG2, PRKAA1 | POLB 3111/4885ALDH1A1 2770/4885MAPT 2764/4885 |
| US-20260029783-A1 | AUTOMATIC PRODUCT DETECTION AND MODEL SWITCHING | SAMM50, TMEM120A, O60361 | POLB 1909/4885ALDH1A1 3465/4885MAPT 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.