Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924637 | 0.85 | MAPT (0.33) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL24484539 | 0.72 | MAPT (0.41) | MAPTMEN1KMT2AKDM4EHIF1A | |
| SCHEMBL2896109 | 0.71 | MAPK1 (0.39) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL20044004 | 0.70 | — | — | |
| SCHEMBL19351826 | 0.70 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1HTTRECQL | |
| SCHEMBL257288 | 0.70 | — | — | |
| SCHEMBL30102547 | 0.68 | BPTF (0.36) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL21896579 | 0.68 | MAPK1 (0.38) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| Methane SCHEMBL28928106 | 0.68 | MAPK1 (0.38) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL24070657 | 0.68 | BPTF (0.36) | MAPTMEN1KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065356-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | WO | disclosed |