SCHEMBL257288

SCHEMBL257288

N#Cc1c(C#N)c(Br)c2nsnc2c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19351893 0.88
SCHEMBL31290789 0.71 ATM (0.37)
SCHEMBL19351826 0.70 ALDH1A1 (0.33)
SCHEMBL20044004 0.70
SCHEMBL20050520 0.70 MAPT (0.33)
SCHEMBL11480603 0.68 ATM (0.36)
SCHEMBL30983774 0.68 ATM (0.36)
SCHEMBL24829509 0.65 ALDH1A1 (0.30)
SCHEMBL5655492 0.65 MEN1 (0.32)
SCHEMBL2832396 0.65 MAPT (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837613-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2017-12-05 US disclosed
US-9837613-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2017-12-05 US disclosed
US-20170327634-A1 PREPARATION OF POLYMERS COMPRISING AT LEAST ONE BENZO[C][1,2,5]THIADIAZOL-5,6-DICARBONITRILE-UNIT BASF SE (DE) 2017-11-16 US disclosed
WO-2016083303-A1 PREPARATION OF POLYMERS COMPRISING AT LEAST ONE BENZO[C][1,2,5]THIADIAZOL-5,6-DICARBONITRILE-UNIT BASF SE (DE) 2016-06-02 WO disclosed
US-9153784-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2015-10-06 US disclosed
US-9153784-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2015-10-06 US disclosed
US-20150270490-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
US-20150270490-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
US-20130161567-A1 CONJUGATED POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-27 US disclosed
US-20130161567-A1 CONJUGATED POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-27 US disclosed
WO-2012028246-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed