Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951077 | 0.85 | HDAC1 (0.70) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL15551749 | 0.83 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL2131564 | 0.83 | HDAC1 (0.55) | HDAC1HDAC2HDAC3KEAP1 | |
| SCHEMBL15938678 | 0.83 | HDAC1 (0.56) | HDAC1HDAC2HDAC3NCOR2KEAP1 | |
| SCHEMBL24203549 | 0.82 | HDAC1 (0.73) | HDAC1HDAC2HDAC3 | |
| SCHEMBL8955980 | 0.81 | SMN1; SMN2 (0.55) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL30748254 | 0.81 | SMN1; SMN2 (0.55) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL1708819 | 0.81 | HDAC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL8110762 | 0.81 | HDAC2 (0.83) | HDAC1HDAC2HDAC3 | |
| SCHEMBL1887376 | 0.79 | KMT2A (0.59) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-07-17 | — | — | US | disclosed |
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| US-11981665-B2 | Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof | CHEN ZHIHONG (US) | 2024-05-14 | — | — | US | disclosed |
| CN-111683662-B | Substituted pyrimidine compounds, pharmaceutical compositions and methods of treatment | 陈志宏 | 2024-04-02 | — | — | CN | disclosed |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2024-04-02 | — | — | US | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230109688-A1 | SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | CHEN ZHIHONG (US) | 2023-04-13 | — | — | US | disclosed |
| EP-3675860-B1 | SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | ZHIHONG CHEN (US) | 2023-03-08 | — | — | EP | disclosed |
| US-11440904-B2 | Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof | CHEN ZHIHONG (US) | 2022-09-13 | — | — | US | disclosed |
| EP-3971166-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Corteva Agriscience LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| US-20200190068-A1 | SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | CHEN ZHIHONG (US) | 2020-06-18 | — | — | US | disclosed |
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-20190150452-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-20190150452-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-10258045-B2 | Molecules having pesticidal utility and intermediates, compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-04-16 | — | — | US | disclosed |
| US-10258045-B2 | Molecules having pesticidal utility and intermediates, compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-04-16 | — | — | US | disclosed |
| WO-2019046163-A1 | SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | ZHIHONG CHEN (US) | 2019-03-07 | — | — | WO | disclosed |
| US-20180098541-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-12 | — | — | US | disclosed |
| US-20180098541-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098541-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | HDAC1 3295/4885HDAC2 2950/4885HDAC3 3300/4885 |
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | HDAC1 3169/4885HDAC2 2995/4885HDAC3 3402/4885 |
| US-20200190068-A1 | SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | BTK, PTK2, LCK | HDAC1 2735/4885HDAC2 1615/4885HDAC3 2190/4885 |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | HDAC1 3044/4885HDAC2 2568/4885HDAC3 3070/4885 |
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | HDAC1 3044/4885HDAC2 2568/4885HDAC3 3070/4885 |
| US-20230109688-A1 | SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | BTK, PTK2, LCK | HDAC1 2735/4885HDAC2 1615/4885HDAC3 2190/4885 |
| US-11981665-B2 | Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof | BTK, PTK2, LCK | HDAC1 2735/4885HDAC2 1615/4885HDAC3 2190/4885 |
| US-11440904-B2 | Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof | BTK, PTK2, LCK | HDAC1 2735/4885HDAC2 1615/4885HDAC3 2190/4885 |
| US-10258045-B2 | Molecules having pesticidal utility and intermediates, compositions and processes related thereto | ACHE, DDT, MLYCD | HDAC1 3214/4885HDAC2 2845/4885HDAC3 3137/4885 |
| US-20190150452-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | HDAC1 3295/4885HDAC2 2950/4885HDAC3 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.