Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ODC1 | P11926 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.34 |
| ▸ | TLR3 | O15455 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20051767 | 0.94 | TYR (0.38) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL20051750 | 0.93 | CNR2 (0.40) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL23398012 | 0.92 | CNR2 (0.42) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL21254262 | 0.89 | TYR (0.38) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL21254126 | 0.88 | ACHE (0.41) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL21254269 | 0.88 | TYR (0.37) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL21254071 | 0.88 | TYR (0.37) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL20051755 | 0.85 | TYR (0.36) | TYRODC1HSP90AA1TP53CYP3A4 | |
| SCHEMBL23017796 | 0.84 | TYR (0.39) | TYRODC1SMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL23398016 | 0.83 | CNR1 (0.35) | TYRODC1HSP90AA1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524609-B1 | PROCESS FOR THE PREPARATION OF 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVES, OPTICAL ISOMERS THEREOF, AND INTERMEDIATES OF THE PROCESS | GLACEUM INC (KR) | 2021-05-26 | — | — | EP | disclosed |
| US-10947250-B2 | 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof | GLACEUM, INC. | 2021-03-16 | — | — | US | disclosed |
| US-20210040106-A1 | METHOD FOR SYNTHESIZING 3-PHENYL-2,8-DIHYDROPYRANO [2,3-F] CHROMENE DERIVATIVE | Glaceum Inc. (KR) | 2021-02-11 | — | — | US | disclosed |
| US-20200199142-A1 | 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF | GLACEUM INC (KR) | 2020-06-25 | — | — | US | disclosed |
| US-10669282-B2 | Method for synthesizing 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2.3-f]chromene derivative and optical isomer of thereof | GLACEUM, INC. (KR) | 2020-06-02 | — | — | US | disclosed |
| US-20200048272-A1 | 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF | GLACEUM, INC. (KR) | 2020-02-13 | — | — | US | disclosed |
| WO-2019194582-A1 | METHOD FOR SYNTHESIZING 3-PHENYL-2,8-DIHYDROPYRANO [2,3-F] CHROMENE DERIVATIVE | 주식회사 글라세움 | 2019-10-10 | — | — | WO | disclosed |
| EP-3524609-A1 | 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF | Glaceum, Inc. (KR) | 2019-08-14 | — | — | EP | disclosed |
| WO-2018066872-A1 | 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF | 주식회사 글라세움 | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669282-B2 | Method for synthesizing 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2.3-f]chromene derivative and optical isomer of thereof | CYP2J2, CYP2A13, HPD | TYR 23/4885ODC1 1009/4885HSP90AA1 4806/4885 |
| US-20200199142-A1 | 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF | CYP2J2, HPD, CYP2A13 | TYR 53/4885ODC1 1888/4885HSP90AA1 4569/4885 |
| US-20200048272-A1 | 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF | CYP2J2, HPD, CYP2A13 | TYR 53/4885ODC1 1888/4885HSP90AA1 4569/4885 |
| US-10947250-B2 | 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof | CYP2J2, HPD, CYP2A13 | TYR 53/4885ODC1 1888/4885HSP90AA1 4569/4885 |
| US-20210040106-A1 | METHOD FOR SYNTHESIZING 3-PHENYL-2,8-DIHYDROPYRANO [2,3-F] CHROMENE DERIVATIVE | HPD, CYP2J2, PAH | TYR 12/4885ODC1 2294/4885HSP90AA1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.