Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867643 | 0.92 | MAPT (0.41) | MAPTMAPK8ABL1TSHRHTT | |
| SCHEMBL13443479 | 0.86 | MAPT (0.45) | MAPTMAPK8TSHRHTTHSD17B10 | |
| SCHEMBL20051999 | 0.84 | POLB (0.43) | MAPTABL1TSHRHTTHSD17B10 | |
| SCHEMBL15763376 | 0.79 | MAPT (0.50) | MAPTMAPK8ABL1TSHRHTT | |
| SCHEMBL14867647 | 0.78 | POLB (0.41) | MAPTABL1TSHRHTTHSD17B10 | |
| SCHEMBL15948778 | 0.72 | MEN1 (0.34) | ABL1 | |
| SCHEMBL15677320 | 0.72 | — | — | |
| SCHEMBL13443489 | 0.72 | POLB (0.48) | MAPTMAPK8ABL1TSHRHTT | |
| SCHEMBL16575817 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL16576402 | 0.71 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944929-B2 | UNA single stranded oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |