Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 5/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867637 | 0.93 | POLB (0.68) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL23710595 | 0.89 | POLB (0.85) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL24772316 | 0.89 | POLB (0.68) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL23710643 | 0.89 | POLB (0.68) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL13443477 | 0.87 | POLB (0.79) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL25611288 | 0.84 | POLB (0.84) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL25583967 | 0.83 | POLB (0.69) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL20754501 | 0.82 | POLB (0.62) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL20407952 | 0.81 | POLB (0.55) | POLBHSD17B10ALDH1A1DUTLMNA | |
| SCHEMBL20052004 | 0.81 | POLB (0.55) | POLBHSD17B10ALDH1A1DUTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944929-B2 | UNA single stranded oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |