Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17041835 | 0.81 | TDP1 (0.53) | TDP1DAOCRBNMAPK1TK1 | |
| SCHEMBL29224874 | 0.75 | TDP1 (0.47) | TDP1DAOCRBNMAPK1SMN1; SMN2 | |
| SCHEMBL18870686 | 0.72 | TDP1 (0.52) | TDP1DAOCRBN | |
| SCHEMBL29135925 | 0.71 | TDP1 (0.47) | TDP1DAOCRBN | |
| SCHEMBL646139 | 0.70 | TDP1 (0.59) | TDP1CRBNMAPK1TK1 | |
| SCHEMBL17040216 | 0.68 | TDP1 (0.52) | TDP1DAOCRBNSMN1; SMN2 | |
| SCHEMBL21283036 | 0.68 | TDP1 (0.43) | TDP1DAOCRBNSMN1; SMN2 | |
| SCHEMBL8303043 | 0.67 | TDP1 (0.45) | TDP1DAOCRBN | |
| SCHEMBL18871230 | 0.66 | TDP1 (0.41) | TDP1DAO | |
| SCHEMBL21283135 | 0.66 | MAPK1 (0.33) | TDP1DAOMAPK1TK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |