Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18870686 | 0.75 | TDP1 (0.52) | TDP1CRBNDAO | |
| SCHEMBL15422063 | 0.70 | — | — | |
| SCHEMBL20052235 | 0.67 | TDP1 (0.47) | TDP1CRBNDAO | |
| SCHEMBL17041835 | 0.64 | TDP1 (0.53) | TDP1CRBNDAOHPGDPOLB | |
| SCHEMBL18858880 | 0.63 | TDP1 (0.52) | TDP1CRBNTYMPDAOBLM | |
| SCHEMBL17040216 | 0.63 | TDP1 (0.52) | TDP1CRBNALDH1A1DAOHPGD | |
| SCHEMBL400005 | 0.62 | TDP1 (1.00) | TDP1CRBNALDH1A1POLB | |
| SCHEMBL9190653 | 0.62 | TDP1 (0.57) | TDP1CRBNTYMPBLM | |
| SCHEMBL9192590 | 0.62 | TDP1 (0.57) | TDP1CRBNALDH1A1HPGDLMNA | |
| SCHEMBL13806371 | 0.58 | CA12 (0.50) | TDP1CRBNALDH1A1HPGDFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604365-B1 | Imidazole derivatives and their use as agrochemical agents | NOVARTIS AG (CH) | 1999-05-26 | — | — | EP | disclosed |
| US-5679623-A | PESTICIDES, INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0604365-A1 | Imidazole derivatives and their use as agrochemical agents | CIBA-GEIGY AG (CH) | 1994-06-29 | — | — | EP | disclosed |