Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 15/20 | 0.77 |
| ▸ | CASP7 | P55210 | 9/20 | 0.77 |
| ▸ | CASP1 | P29466 | 7/20 | 0.77 |
| ▸ | CASP9 | P55211 | 4/20 | 0.70 |
| ▸ | CASP4 | P49662 | 3/20 | 0.70 |
| ▸ | CASP5 | P51878 | 2/20 | 0.70 |
| ▸ | CASP6 | P55212 | 2/20 | 0.70 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.70 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.70 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | NMBR | P28336 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462676 | 1.00 | CASP3 (0.77) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20355933 | 1.00 | CASP3 (0.77) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL7969748 | 0.95 | CASP3 (0.83) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462653 | 0.90 | CASP3 (0.92) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL7887099 | 0.88 | CASP3 (0.76) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20609292 | 0.87 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL12829768 | 0.87 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20355910 | 0.86 | NMBR (0.61) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052375 | 0.86 | NMBR (0.61) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462702 | 0.86 | NMBR (0.61) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |