Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.61 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CASP4 | P49662 | 1/20 | 0.55 |
| ▸ | CASP5 | P51878 | 1/20 | 0.55 |
| ▸ | CASP9 | P55211 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.55 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462702 | 1.00 | NMBR (0.61) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL20355910 | 1.00 | NMBR (0.61) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL7971055 | 0.92 | CASP1 (0.63) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL20052368 | 0.91 | NMBR (0.56) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL20355932 | 0.91 | NMBR (0.56) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL15462644 | 0.91 | NMBR (0.56) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL19944561 | 0.89 | NMBR (0.64) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL20355933 | 0.86 | CASP3 (0.77) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL20052417 | 0.86 | CASP3 (0.77) | NMBRSIRT5CASP1CASP3CASP7 | |
| SCHEMBL15462676 | 0.86 | CASP3 (0.77) | NMBRSIRT5CASP1CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |