Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27927404 | 0.83 | HTR2A (0.39) | OPRL1HTR2AHTR2CHTR2BLDHA | |
| SCHEMBL24970171 | 0.80 | MEN1 (0.34) | OPRM1OPRL1HTR2AHTR2CHTR2B | |
| SCHEMBL21850006 | 0.80 | SLC6A2 (0.32) | — | |
| SCHEMBL20052998 | 0.80 | CTSB (0.32) | — | |
| SCHEMBL20052995 | 0.80 | POLL (0.37) | HTR2AHTR2CHTR2BADRA2AADRA1A | |
| SCHEMBL20053013 | 0.77 | — | — | |
| SCHEMBL4317902 | 0.72 | SMN1; SMN2 (0.43) | OPRL1HTR2AHTR2CHTR2BLDHA | |
| SCHEMBL4319533 | 0.72 | SMN1; SMN2 (0.43) | OPRL1HTR2AHTR2CHTR2BLDHA | |
| SCHEMBL17158612 | 0.70 | TAAR1 (0.43) | — | |
| SCHEMBL17158510 | 0.70 | MAP3K14 (0.41) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |