Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052967 | 0.84 | HTR1A (0.37) | POLLHTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL20052932 | 0.80 | OPRM1 (0.32) | HTR2CHTR2AHTR2BADRA2AADRA1A | |
| SCHEMBL20052998 | 0.79 | CTSB (0.32) | — | |
| SCHEMBL21850006 | 0.76 | SLC6A2 (0.32) | KMT2ASLC6A2SLC6A4 | |
| SCHEMBL20053013 | 0.73 | — | — | |
| SCHEMBL9303942 | 0.70 | ACHE (0.45) | SLC6A2SLC6A4 | |
| SCHEMBL29041073 | 0.70 | HTR2C (0.51) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL17710161 | 0.69 | KDM4E (0.44) | — | |
| SCHEMBL9301911 | 0.69 | CA1 (0.39) | HTR2ASLC6A2SLC6A4 | |
| SCHEMBL9302902 | 0.69 | TTR (0.40) | MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |