Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935836 | 0.85 | ACACB (0.60) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20053017 | 0.80 | MAPT (0.45) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20220481 | 0.77 | ADORA2B (0.47) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14944976 | 0.77 | ACACB (0.71) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14945674 | 0.76 | ACACB (0.49) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14945673 | 0.74 | ACACB (0.57) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14948749 | 0.71 | ADORA2B (0.58) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20053003 | 0.71 | ADORA2B (0.54) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20651099 | 0.71 | ACACB (0.53) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20220430 | 0.71 | ADORA2B (0.54) | ADORA2BACACBACACAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |