Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019755 | 0.88 | ALDH1A1 (0.38) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL17219 | 0.81 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL14860830 | 0.77 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL10948478 | 0.75 | MEN1 (0.48) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL5655081 | 0.74 | ALDH1A1 (0.65) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL11594862 | 0.74 | EPHX1 (0.60) | KMT2AMEN1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL11141423 | 0.74 | EPHX1 (0.60) | KMT2AMEN1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL11596181 | 0.74 | EPHX1 (0.60) | KMT2AMEN1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL11053795 | 0.74 | EPHX1 (0.60) | KMT2AMEN1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL11596632 | 0.74 | EPHX1 (0.60) | KMT2AMEN1SMN1; SMN2LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944770-B2 | Moisture curable compound with thiourea | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-04-17 | — | — | US | disclosed |