Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666733 | 1.00 | ALDH1A1 (0.65) | ALDH1A1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20204692 | 0.93 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17219 | 0.92 | KMT2A (0.57) | ALDH1A1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8396753 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HRH4HRH2EPHX2 | |
| SCHEMBL11594299 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HRH4HRH2EPHX2 | |
| SCHEMBL11596858 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HRH4HRH2EPHX2 | |
| SCHEMBL11594821 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HRH4HRH2EPHX2 | |
| SCHEMBL14860830 | 0.87 | KMT2A (0.53) | ALDH1A1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11053795 | 0.85 | EPHX1 (0.60) | MEN1KMT2ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL11594862 | 0.85 | EPHX1 (0.60) | MEN1KMT2ASMN1; SMN2LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301042-B2 | Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-11-27 | — | — | US | disclosed |
| US-20030199619-A1 | Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions | CROMPTON CORPORATION | 2003-10-23 | — | — | US | disclosed |