Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18723237 | 0.98 | TSHR (0.59) | TSHRLMNAOPRM1ALDH1A1TDP1 | |
| SCHEMBL18723189 | 0.98 | TSHR (0.59) | TSHRLMNAOPRM1ALDH1A1TDP1 | |
| SCHEMBL7765607 | 0.93 | TSHR (0.54) | TSHRLMNAOPRM1DNM1FDPS | |
| SCHEMBL7761911 | 0.93 | TSHR (0.54) | TSHRLMNAOPRM1DNM1FDPS | |
| SCHEMBL18723240 | 0.93 | TSHR (0.59) | TSHRLMNAOPRM1DNM1THRB | |
| SCHEMBL24919784 | 0.91 | TSHR (0.56) | TSHRLMNAOPRM1ALDH1A1DNM1 | |
| SCHEMBL20869954 | 0.91 | TSHR (0.56) | TSHRLMNAOPRM1ALDH1A1DNM1 | |
| SCHEMBL18638734 | 0.91 | TSHR (0.56) | TSHRLMNAALDH1A1TDP1DNM1 | |
| SCHEMBL19649667 | 0.88 | TSHR (0.52) | TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL17970381 | 0.88 | TSHR (0.59) | TSHRLMNAALDH1A1TDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944638-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND US (IE) | 2018-04-17 | — | — | US | disclosed |