SCHEMBL7765607

SCHEMBL7765607

CCCCCCCCC(CCC)CCCC#N

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
LMNA P02545 1/20 0.46
DNM1 Q05193 2/20 0.36
THRB P10828 1/20 0.35
OPRM1 P35372 1/20 0.34
GPR84 Q9NQS5 3/20 0.33
FDPS P14324 3/20 0.33
SPHK1 Q9NYA1 1/20 0.33
FFAR1 O14842 1/20 0.33
HMGCR P04035 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761911 1.00 TSHR (0.54) TSHRLMNADNM1THRBOPRM1
SCHEMBL18723237 0.96 TSHR (0.59) TSHRLMNADNM1THRBOPRM1
SCHEMBL18723189 0.96 TSHR (0.59) TSHRLMNADNM1THRBOPRM1
SCHEMBL20053307 0.93 TSHR (0.62) TSHRLMNADNM1THRBOPRM1
SCHEMBL18723240 0.91 TSHR (0.59) TSHRLMNADNM1THRBOPRM1
SCHEMBL19649667 0.91 TSHR (0.52) TSHRLMNA
SCHEMBL24919784 0.89 TSHR (0.56) TSHRLMNADNM1THRBOPRM1
SCHEMBL20869954 0.89 TSHR (0.56) TSHRLMNADNM1THRBOPRM1
SCHEMBL18638734 0.89 TSHR (0.56) TSHRLMNADNM1THRBHMGCR
SCHEMBL11086025 0.89 TSHR (0.55) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092420-A2 PERYLENE DYES WITH PERSISTENT FLUORESCENCE CAUSED BY STERIC INHIBITION OF AGGREGATION RADIANT COLOR N.V. (BE) 2001-12-06 WO disclosed