Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860462 | 1.00 | DUT (0.45) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL860463 | 1.00 | DUT (0.45) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL18672024 | 0.91 | DUT (0.46) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL21063983 | 0.91 | DUT (0.46) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL17560698 | 0.89 | DUT (0.54) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL21418793 | 0.89 | DUT (0.54) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL21755901 | 0.89 | DUT (0.47) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL12701381 | 0.86 | DUT (0.45) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL18269224 | 0.85 | SLC28A1 (0.49) | SLC29A1SLC28A1SLC28A2SLC28A3P2RY2 | |
| SCHEMBL29414441 | 0.85 | SLC28A1 (0.46) | DUTSLC29A1SLC28A1SLC28A2SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943604-B2 | Targeted therapeutic nucleosides and their use | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-17 | — | — | US | disclosed |