Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560698 | 0.92 | DUT (0.54) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL21418793 | 0.92 | DUT (0.54) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL20053425 | 0.89 | DUT (0.45) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL860462 | 0.89 | DUT (0.45) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL860463 | 0.89 | DUT (0.45) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL21755900 | 0.87 | P2RY2 (0.46) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL767728 | 0.87 | P2RY2 (0.46) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL17739537 | 0.84 | DUT (0.46) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL17739531 | 0.83 | CYP3A4 (0.40) | DUTP2RY2P2RY4POLA1CYP3A4 | |
| SCHEMBL19813714 | 0.82 | DUT (0.52) | DUTP2RY2P2RY4POLA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613753-A1 | LIVER-SPECIFIC DELIVERY-BASED ANTI-HEPATITIS C PRECURSOR DRUG NUCLEOSIDE CYCLOPHOSPHATE COMPOUND AND USE | Zhejiang Palo Alto Pharmaceuticals, Inc (CN) | 2020-02-26 | — | — | EP | disclosed |