SCHEMBL2005344

SCHEMBL2005344

CC(CC(=O)Cl)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.51
HPGD P15428 3/20 0.50
ALDH1A1 P00352 2/20 0.50
RAB9A P51151 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
POLB P06746 2/20 0.49
BCHE P06276 1/20 0.49
TAAR1 Q96RJ0 2/20 0.48
TRPA1 O75762 2/20 0.47
NPC1 O15118 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
LTB4R Q15722 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5787675 1.00 FFAR1 (0.51) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL5785245 1.00 FFAR1 (0.51) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL21237722 0.89 PTGS2 (0.55) FFAR1CYP2C19
SCHEMBL21237726 0.89 PTGS2 (0.55) FFAR1CYP2C19
SCHEMBL11142933 0.84 FFAR1 (0.49) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL237090 0.83 FFAR1 (0.70) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL7398650 0.83 ACHE (0.60) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL237091 0.83 FFAR1 (0.70) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL11399936 0.83 ACHE (0.60) FFAR1HPGDALDH1A1RAB9ACYP3A4
SCHEMBL1149768 0.83 FFAR1 (0.70) FFAR1HPGDALDH1A1RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150349-A1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS FORMA THERAPEUTICS, INC. (US) 2024-05-09 US disclosed
EP-3681885-B1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS FORMA THERAPEUTICS INC (US) 2024-02-28 EP disclosed
EP-3681885-B1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS FORMA THERAPEUTICS INC (US) 2024-02-28 EP disclosed
US-11787803-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors FORMA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-11787803-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors FORMA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-11787803-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors FORMA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-20220169647-A1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS FORMA THERAPEUTICS, INC. 2022-06-02 US disclosed
US-20220169647-A1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS FORMA THERAPEUTICS, INC. 2022-06-02 US disclosed
US-11292791-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors FORMA THERAPEUTICS, INC. (US) 2022-04-05 US disclosed
US-11292791-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors FORMA THERAPEUTICS, INC. (US) 2022-04-05 US disclosed
EP-0079049-B1 NOVEL SUBSTITUTED ALKANOYLIMIDAZOL-2-ONE DERIVATIVES MERRELL DOW PHARMACEUTICALS INC. (US) 1987-04-01 EP disclosed
US-4447619-A CARDIOTONIC AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1984-05-08 US disclosed
EP-0079049-A2 Novel substituted alkanoylimidazol-2-one derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1983-05-18 EP disclosed
US-4367236-A CARDIOTONIC AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1983-01-04 US disclosed
US-4198519-A Anti-inflammatory compounds BEECHAM GROUP LIMITED (GB) 1980-04-15 US disclosed
US-4192883-A ANTITUSSIVES PIERRE FABRE, S.A. (FR) 1980-03-11 US disclosed
US-4153718-A Anti-inflammatory compounds BEECHAM GROUP LIMITED (GB) 1979-05-08 US disclosed
US-4122199-A Amides of pyrrolidinoethylamine which can be used in treatment of coughs PIERRE FABRE S.A. (FR) 1978-10-24 US disclosed
US-4113680-A Method for preparing 17 α-ester-21-halo pregnanes TAISHO PHARMACEUTICAL CO., LTD. (JP) 1978-09-12 US disclosed
US-3992396-A TRANQUILIZERS, HYPNOTICS SANDOZ, INC. (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11292791-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors EP300, CREBBP, BRD3 FFAR1 3803/4885HPGD 2119/4885ALDH1A1 3405/4885
US-20240150349-A1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS EP300, CREBBP, BRD3 FFAR1 3803/4885HPGD 2119/4885ALDH1A1 3405/4885
US-20220169647-A1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS EP300, CREBBP, BRD3 FFAR1 3803/4885HPGD 2119/4885ALDH1A1 3405/4885
US-11787803-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors EP300, CREBBP, BRD3 FFAR1 3803/4885HPGD 2119/4885ALDH1A1 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.