Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539327 | 0.92 | GPR119 (0.50) | GPR119HRH3CYP4F2CYP4A11HPGDS | |
| SCHEMBL15539331 | 0.92 | GPR119 (0.50) | GPR119HRH3CYP4F2CYP4A11HPGDS | |
| SCHEMBL20053619 | 0.91 | GPR119 (0.60) | GPR119HRH3CYP4F2CYP4A11HPGD | |
| SCHEMBL21534646 | 0.90 | GPR119 (0.59) | GPR119HRH3CYP4F2CYP4A11HPGD | |
| SCHEMBL16769011 | 0.90 | GPR119 (0.51) | GPR119HRH3CYP4F2CYP4A11HPGDS | |
| SCHEMBL15538422 | 0.89 | GPR119 (0.51) | GPR119CYP4F2CYP4A11HPGDSSMN1; SMN2 | |
| SCHEMBL21534807 | 0.88 | GPR119 (0.43) | GPR119HRH3HPGDKDM4EL3MBTL1 | |
| SCHEMBL15539367 | 0.88 | GPR119 (0.53) | GPR119CYP4F2CYP4A11HPGDSSMN1; SMN2 | |
| SCHEMBL21535116 | 0.88 | GPR119 (0.49) | GPR119HRH3CYP4F2CYP4A11HPGDS | |
| SCHEMBL20053543 | 0.88 | GPR119 (0.54) | GPR119CYP4F2CYP4A11HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |