Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 13/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | GYS1 | P13807 | 3/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053730 | 0.93 | PDK2 (0.40) | PDK2KDM1AXDHGYS1SPHK2 | |
| SCHEMBL16803827 | 0.92 | PDK2 (0.45) | PDK2GYS1SPHK2SPHK1 | |
| SCHEMBL20053699 | 0.91 | XDH (0.42) | PDK2XDHSPHK2SPHK1 | |
| SCHEMBL20053561 | 0.91 | XDH (0.39) | PDK2KDM1AXDH | |
| SCHEMBL16803854 | 0.90 | PDK2 (0.42) | PDK2KDM1AGYS1SPHK2SPHK1 | |
| SCHEMBL16803855 | 0.90 | PDK2 (0.42) | PDK2KDM1AGYS1SPHK2SPHK1 | |
| SCHEMBL15539792 | 0.88 | CNR2 (0.37) | PDK2XDHGYS1 | |
| SCHEMBL20053538 | 0.88 | XDH (0.38) | XDH | |
| SCHEMBL16803826 | 0.87 | PDK2 (0.46) | PDK2GYS1SPHK2SPHK1 | |
| SCHEMBL15539543 | 0.87 | PDK2 (0.40) | PDK2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |