Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053586 | 0.92 | XDH (0.41) | XDHSPHK1SPHK2METPDK2 | |
| SCHEMBL20053560 | 0.91 | PDK2 (0.42) | XDHSPHK1SPHK2PDK2 | |
| SCHEMBL20053538 | 0.90 | XDH (0.38) | XDHCNR2 | |
| SCHEMBL16777086 | 0.89 | CNR2 (0.43) | XDHCNR2 | |
| SCHEMBL15539745 | 0.89 | CNR2 (0.43) | XDHCNR2 | |
| SCHEMBL16768915 | 0.89 | XDH (0.38) | XDHMETCNR2 | |
| SCHEMBL20053663 | 0.88 | XDH (0.40) | XDHCNR2 | |
| SCHEMBL15539543 | 0.88 | PDK2 (0.40) | XDHPDK2CNR2 | |
| SCHEMBL16803849 | 0.87 | CNR2 (0.41) | SPHK1SPHK2METPDK2HTR1A | |
| SCHEMBL16803848 | 0.87 | CNR2 (0.41) | SPHK1SPHK2METPDK2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |