Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539449 | 0.91 | KMT2A (0.39) | — | |
| SCHEMBL15539448 | 0.91 | KMT2A (0.39) | — | |
| SCHEMBL15538866 | 0.89 | KCNH2 (0.43) | HPGDSRBP4KCNH2 | |
| SCHEMBL20053605 | 0.88 | HRH3 (0.44) | HPGDADRB2HRH3ALDH1A1RBP4 | |
| SCHEMBL15539618 | 0.87 | GRM2 (0.41) | HPGDSGPR119KCNH2 | |
| SCHEMBL15538274 | 0.87 | PDK2 (0.40) | ALDH1A1KDM4EL3MBTL1CNR2 | |
| SCHEMBL15538266 | 0.87 | PDK2 (0.40) | ALDH1A1KDM4EL3MBTL1CNR2 | |
| SCHEMBL20053594 | 0.82 | GPR119 (0.46) | ADRB2HRH3RBP4GPR119 | |
| SCHEMBL15538828 | 0.81 | GRM3 (0.42) | HPGDHRH3ALDH1A1KCNH2 | |
| SCHEMBL15538830 | 0.81 | GRM3 (0.42) | HPGDHRH3ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |