Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534646 | 0.95 | GPR119 (0.59) | GPR119HRH3CYP2D6HPGD | |
| SCHEMBL20053619 | 0.94 | GPR119 (0.60) | GPR119HRH3HPGDSHPGD | |
| SCHEMBL15537802 | 0.91 | GPR119 (0.48) | GPR119HRH3HPGDS | |
| SCHEMBL15539385 | 0.91 | GPR119 (0.48) | GPR119HRH3HPGDS | |
| SCHEMBL15538721 | 0.90 | HRH3 (0.55) | HRH3HPGDALDH1A1 | |
| SCHEMBL15537715 | 0.89 | HRH3 (0.56) | GPR119HRH3HPGDALDH1A1 | |
| SCHEMBL16803798 | 0.88 | GPR119 (0.46) | GPR119HPGDSSTAT3 | |
| SCHEMBL15539134 | 0.88 | GPR119 (0.50) | GPR119HPGDS | |
| SCHEMBL15539154 | 0.87 | GPR119 (0.53) | GPR119HRH3HPGDS | |
| SCHEMBL15538942 | 0.87 | GPR119 (0.53) | GPR119HRH3HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |