Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535076 | 0.98 | HRH3 (0.42) | HRH3CYP2D6GPR119SCN9AACHE | |
| SCHEMBL21534975 | 0.97 | HRH3 (0.40) | HRH3CYP2D6GPR119SCN9AACHE | |
| SCHEMBL15537945 | 0.97 | HRH3 (0.42) | HRH3CYP2D6GPR119SCN9AACHE | |
| SCHEMBL15539179 | 0.96 | CYP2D6 (0.43) | HRH3CYP2D6GPR119SCN9AACHE | |
| SCHEMBL15538584 | 0.94 | GPR119 (0.40) | HRH3CYP2D6GPR119SCN9AACHE | |
| SCHEMBL15538379 | 0.93 | SCN9A (0.45) | HRH3GPR119SCN9AACHE | |
| SCHEMBL15537646 | 0.93 | SCN9A (0.45) | HRH3GPR119SCN9AACHE | |
| SCHEMBL15537647 | 0.93 | SCN9A (0.45) | HRH3GPR119SCN9AACHE | |
| SCHEMBL15550849 | 0.92 | GABRA5 (0.43) | HRH3GPR119SCN9AACHELIPE | |
| SCHEMBL15550846 | 0.92 | GABRA5 (0.43) | HRH3GPR119SCN9AACHELIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |