Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20461218 | 0.83 | BTK (0.40) | BTK | |
| SCHEMBL20461116 | 0.81 | BTK (0.61) | BTK | |
| SCHEMBL20461147 | 0.81 | BTK (0.49) | BTK | |
| SCHEMBL20461040 | 0.80 | BTK (0.48) | BTK | |
| SCHEMBL20053917 | 0.80 | AAK1 (0.47) | BTK | |
| SCHEMBL20053966 | 0.79 | BTK (0.52) | BTK | |
| SCHEMBL20461005 | 0.79 | BTK (0.52) | BTKEPHX2 | |
| SCHEMBL20053910 | 0.79 | BTK (0.52) | BTKEPHX2 | |
| SCHEMBL20053939 | 0.79 | BTK (0.47) | BTK | |
| SCHEMBL20053949 | 0.79 | BTK (0.47) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080103-B1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN MA INC (US) | 2018-04-18 | — | — | EP | disclosed |