Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053949 | 0.89 | BTK (0.47) | BTKAKT3 | |
| SCHEMBL16794298 | 0.85 | BTK (0.63) | BTKITGB3ITGA2BAKT3 | |
| SCHEMBL16793879 | 0.80 | BTK (0.70) | BTK | |
| SCHEMBL20461116 | 0.79 | BTK (0.61) | BTKAKT3 | |
| SCHEMBL16793953 | 0.79 | BTK (0.63) | BTKITGB3ITGA2BAKT3 | |
| SCHEMBL20053904 | 0.79 | BTK (0.51) | BTK | |
| SCHEMBL16793695 | 0.77 | BTK (0.53) | BTK | |
| SCHEMBL20461218 | 0.77 | BTK (0.40) | BTK | |
| SCHEMBL20461040 | 0.75 | BTK (0.48) | BTK | |
| SCHEMBL20053969 | 0.75 | MAPK1 (0.34) | BTKAKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080103-B1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN MA INC (US) | 2018-04-18 | — | — | EP | disclosed |