Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114448 | 0.83 | — | — | |
| SCHEMBL15116672 | 0.81 | EPHX2 (0.32) | — | |
| SCHEMBL15113693 | 0.79 | — | — | |
| SCHEMBL20221526 | 0.77 | — | — | |
| SCHEMBL12227075 | 0.76 | POLB (0.43) | ALDH1A1POLBTP53THRBTSHR | |
| SCHEMBL1856287 | 0.76 | KDM4E (0.38) | ALDH1A1POLBTP53THRBTSHR | |
| SCHEMBL31479802 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL12162990 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBTP53THRBLMNA | |
| SCHEMBL26113275 | 0.69 | ALDH1A1 (0.49) | ALDH1A1POLBTP53THRBTSHR | |
| SCHEMBL20855387 | 0.68 | KDM4E (0.42) | ALDH1A1POLBTP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |