Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139884 | 0.89 | ALDH1A1 (0.38) | MGLLALDH1A1USP2MAPTKDM4E | |
| SCHEMBL766819 | 0.82 | — | — | |
| SCHEMBL19619135 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6817054 | 0.68 | — | — | |
| SCHEMBL971398 | 0.68 | GRIN2D (0.33) | HSD17B10 | |
| SCHEMBL29185157 | 0.67 | KDM4E (0.40) | ALDH1A1USP2HSD17B10KDM4EALOX15 | |
| SCHEMBL2283153 | 0.62 | MGLL (0.39) | MGLLALDH1A1USP2CA12CA7 | |
| SCHEMBL14079963 | 0.62 | ALDH1A1 (0.41) | MGLLALDH1A1CA12CA7CA14 | |
| SCHEMBL13049886 | 0.60 | HSD17B10 (0.39) | MGLLALDH1A1CA12HSD17B10KDM4E | |
| SCHEMBL165786 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |