Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054529 | 0.87 | AAK1 (0.46) | AAK1CACNA1HRAD52UBE2NIDO1 | |
| SCHEMBL20054554 | 0.87 | AAK1 (0.46) | AAK1CACNA1HRAD52UBE2NIDO1 | |
| SCHEMBL20054430 | 0.81 | AAK1 (0.41) | AAK1CACNA1HRAD52UBE2NIDO1 | |
| SCHEMBL4354084 | 0.80 | TDP1 (0.70) | CACNA1HRAD52UBE2NIDO1MAPT | |
| SCHEMBL19377986 | 0.80 | HDAC3 (0.52) | CACNA1HRAD52UBE2NIDO1MAPT | |
| SCHEMBL29409142 | 0.80 | TDP1 (0.70) | CACNA1HRAD52UBE2NIDO1MAPT | |
| SCHEMBL38661663 | 0.80 | IDO1 (0.76) | CACNA1HRAD52UBE2NIDO1MAPT | |
| SCHEMBL31733885 | 0.80 | CACNA1H (0.46) | CACNA1HMAPTKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL23705615 | 0.79 | HDAC3 (0.51) | CACNA1HRAD52UBE2NIDO1MAPT | |
| Hydrochloric Acid SCHEMBL5204720 | 0.79 | TDP1 (0.68) | CACNA1HRAD52UBE2NIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |