Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116823 | 1.00 | SSTR3 (0.38) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL20221549 | 1.00 | SSTR3 (0.38) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL16359250 | 0.88 | KMT2A (0.39) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL15116835 | 0.85 | NR1I2 (0.43) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL20054535 | 0.82 | SSTR3 (0.40) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL15116836 | 0.82 | SSTR3 (0.40) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL15114363 | 0.82 | NR1I2 (0.42) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL20054513 | 0.78 | PRMT5 (0.38) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL15116590 | 0.78 | PRMT5 (0.38) | SSTR3KDM4EGLAGAAMAPT | |
| SCHEMBL15116624 | 0.78 | SSTR3 (0.44) | SSTR3TRPA1EPHX2AAK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |