Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116836 | 1.00 | SSTR3 (0.40) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL15116835 | 0.93 | NR1I2 (0.43) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL15114363 | 0.89 | NR1I2 (0.42) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL15116761 | 0.85 | SSTR3 (0.42) | SSTR3AAK1HDAC6 | |
| SCHEMBL15116590 | 0.85 | PRMT5 (0.38) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL20054513 | 0.85 | PRMT5 (0.38) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL16409161 | 0.85 | SSTR3 (0.48) | SSTR3NR1I2AAK1MAPT | |
| SCHEMBL15116823 | 0.82 | SSTR3 (0.38) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL20221549 | 0.82 | SSTR3 (0.38) | SSTR3NR1I2AAK1KDM4EGLA | |
| SCHEMBL20054472 | 0.82 | SSTR3 (0.38) | SSTR3NR1I2AAK1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |