Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22141637 | 1.00 | POLB (0.31) | POLBMEN1KMT2A | |
| SCHEMBL26730949 | 1.00 | POLB (0.31) | POLBMEN1KMT2A | |
| SCHEMBL28381403 | 1.00 | POLB (0.31) | POLBMEN1KMT2A | |
| SCHEMBL28529459 | 0.81 | LMNA (0.33) | MEN1KMT2A | |
| SCHEMBL27813127 | 0.81 | — | — | |
| SCHEMBL20054632 | 0.79 | MAPK1 (0.36) | — | |
| SCHEMBL22127645 | 0.79 | MAPK1 (0.36) | — | |
| SCHEMBL20581981 | 0.79 | MAPK1 (0.36) | — | |
| SCHEMBL20054634 | 0.79 | MAPK1 (0.36) | — | |
| SCHEMBL20221108 | 0.78 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |