Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056114 | 0.75 | SLC6A3 (0.47) | KMT2ACYP3A4ALDH1A1TSHRHPGD | |
| SCHEMBL1782470 | 0.74 | KMT2A (0.40) | KMT2AALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL6651178 | 0.74 | KMT2A (0.40) | KMT2AALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL31499299 | 0.74 | KMT2A (0.40) | KMT2AALDH1A1TSHRCYP2D6LMNA | |
| SCHEMBL1959777 | 0.74 | TSHR (0.46) | KMT2ATSHRHPGDCYP2D6SRC | |
| SCHEMBL2119361 | 0.72 | CYP2D6 (0.46) | ALDH1A1TSHRHPGDCYP2D6SRC | |
| SCHEMBL9243694 | 0.72 | HPGD (0.46) | KMT2ACYP3A4ALDH1A1TSHRHPGD | |
| SCHEMBL7303575 | 0.72 | CYP2D6 (0.46) | ALDH1A1TSHRHPGDCYP2D6SRC | |
| SCHEMBL8468001 | 0.72 | CYP2D6 (0.41) | KMT2ACYP3A4ALDH1A1TSHRHPGD | |
| SCHEMBL11204752 | 0.72 | SMN1; SMN2 (0.45) | KMT2AALDH1A1TSHRCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |