Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537233 | 0.77 | SLC6A3 (0.61) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL14159077 | 0.75 | LMNA (0.40) | CYP1A2CYP2D6EPHX1ALDH1A1HSD17B10 | |
| SCHEMBL6691161 | 0.72 | SLC6A3 (0.56) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL10802988 | 0.72 | SLC6A3 (0.41) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL20054801 | 0.72 | KMT2A (0.46) | CYP2D6ALDH1A1KMT2ALMNAMAPK1 | |
| SCHEMBL5580789 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL4780750 | 0.70 | ALDH1A1 (0.51) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL10788110 | 0.70 | EPHX1 (0.41) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL1782470 | 0.69 | KMT2A (0.40) | SMN1; SMN2EPHX1ALDH1A1KMT2ALMNA | |
| SCHEMBL6651178 | 0.69 | KMT2A (0.40) | SMN1; SMN2EPHX1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097072-A1 | Derivatives of benzylsulfinyl acetamides, their therapeutic use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1983-12-28 | — | — | EP | claimed |