Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21440526 | 0.85 | — | — | |
| SCHEMBL19647089 | 0.84 | — | — | |
| SCHEMBL19647086 | 0.82 | — | — | |
| SCHEMBL20054896 | 0.81 | — | — | |
| SCHEMBL20196335 | 0.78 | — | — | |
| SCHEMBL24015360 | 0.76 | ELANE (0.37) | ELANELMNAHSD17B10 | |
| SCHEMBL106867 | 0.76 | RIPK1 (0.37) | ELANE | |
| SCHEMBL18824136 | 0.73 | ELANE (0.35) | ELANELMNAHSD17B10 | |
| SCHEMBL19105258 | 0.73 | TSHR (0.33) | ELANE | |
| SCHEMBL25070815 | 0.71 | ELANE (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780039-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2018-04-18 | — | — | EP | disclosed |