⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21440526 | 0.85 | — | — | |
| SCHEMBL20196335 | 0.84 | — | — | |
| SCHEMBL20054906 | 0.81 | ELANE (0.38) | — | |
| SCHEMBL19647089 | 0.78 | — | — | |
| SCHEMBL19647086 | 0.77 | — | — | |
| SCHEMBL106867 | 0.72 | RIPK1 (0.37) | — | |
| SCHEMBL19105207 | 0.69 | NR3C1 (0.35) | — | |
| SCHEMBL17281562 | 0.69 | NR3C1 (0.33) | — | |
| SCHEMBL21389209 | 0.67 | DGAT1 (0.34) | — | |
| SCHEMBL12027013 | 0.67 | ELANE (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2021-07-07 | — | — | EP | disclosed |
| EP-2780039-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2018-04-18 | — | — | EP | disclosed |