Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | BRD1 | O95696 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17656218 | 0.96 | ATM (0.43) | RORARORCRORBATML3MBTL1 | |
| SCHEMBL2705512 | 0.90 | ATM (0.47) | RORARORCRORBATML3MBTL1 | |
| SCHEMBL25752331 | 0.84 | ATM (0.46) | RORARORCRORBATML3MBTL1 | |
| SCHEMBL14985669 | 0.82 | ATM (0.43) | RORARORCRORBATML3MBTL1 | |
| SCHEMBL9980158 | 0.82 | ATM (0.43) | RORARORCRORBATML3MBTL1 | |
| SCHEMBL9968161 | 0.81 | ALDH1A1 (0.44) | RORARORCRORBL3MBTL1MEN1 | |
| SCHEMBL8091816 | 0.80 | NPC1 (0.56) | RORARORCRORBATML3MBTL1 | |
| SCHEMBL9976988 | 0.77 | ALDH1A1 (0.51) | RORARORCRORBMEN1KMT2A | |
| SCHEMBL25752342 | 0.74 | ALDH1A1 (0.50) | RORARORCRORBTBK1CASR | |
| SCHEMBL12083593 | 0.74 | GPR3 (0.52) | RORARORCRORBL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |