Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070401 | 0.94 | PARP1 (0.43) | PARP1ALOX5MEN1KMT2AALDH1A1 | |
| SCHEMBL13071140 | 0.86 | PARP1 (0.51) | PARP1ALOX5ALDH1A1KDM4EGAA | |
| SCHEMBL38657363 | 0.86 | ALOX5 (0.41) | ALOX5ALDH1A1GAAHPGD | |
| SCHEMBL2705717 | 0.86 | ALOX5 (0.41) | ALOX5ALDH1A1GAAHPGD | |
| SCHEMBL27344505 | 0.83 | PARP1 (0.45) | PARP1ALOX5ALDH1A1KDM4EGAA | |
| SCHEMBL30811612 | 0.83 | PARP1 (0.45) | PARP1ALOX5ALDH1A1KDM4EGAA | |
| SCHEMBL9980123 | 0.81 | ALDH1A1 (0.38) | ALOX5ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL17656225 | 0.80 | AKR1C3 (0.38) | PARP1MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL30811604 | 0.79 | ALOX5 (0.41) | ALOX5MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27344507 | 0.79 | ALOX5 (0.41) | ALOX5MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |