Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980197 | 0.85 | RAB9A (0.51) | USP7NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL20055110 | 0.85 | AAK1 (0.48) | MEN1KMT2AKDM4EAAK1HSD17B10 | |
| SCHEMBL17656206 | 0.82 | NPC1 (0.46) | USP7NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL20055648 | 0.81 | AAK1 (0.50) | MEN1KMT2AAAK1 | |
| SCHEMBL8746195 | 0.80 | PDE10A (0.49) | — | |
| SCHEMBL13071128 | 0.79 | NPC1 (0.54) | USP7NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL20055644 | 0.79 | AAK1 (0.47) | KDM4EMAPTGAAAAK1 | |
| SCHEMBL15463298 | 0.78 | KMT2A (0.50) | USP7NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL2457137 | 0.78 | RAB9A (0.67) | USP7NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL20054554 | 0.76 | AAK1 (0.46) | MEN1KMT2AKDM4EMAPTAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |