Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706620 | 0.89 | KDM4E (0.50) | KDM4EAAK1HSD17B10SCN10A | |
| SCHEMBL19884296 | 0.86 | NPC1 (0.39) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL9980197 | 0.85 | RAB9A (0.51) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL9980154 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EHPGDAAK1HSD17B10 | |
| SCHEMBL20055644 | 0.84 | AAK1 (0.47) | KDM4EMAPTGAAAAK1 | |
| SCHEMBL20055263 | 0.82 | USP7 (0.47) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL2756562 | 0.80 | KDM4E (0.36) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL17323162 | 0.80 | CNR1 (0.41) | NPC1RAB9APOLBGFERSCN10A | |
| SCHEMBL15443396 | 0.79 | NLN (0.47) | KDM4EHSD17B10 | |
| SCHEMBL2706737 | 0.79 | ALDH1A1 (0.56) | NPC1RAB9APOLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |