Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 9/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.68 |
| ▸ | ERN1 | O75460 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999193 | 0.87 | ERN1 (0.59) | HSD17B1HSD17B2ERN1PARP1CSF1R | |
| SCHEMBL29904856 | 0.85 | HSD17B1 (0.69) | HSD17B1HSD17B2ERN1ESR2HSD17B14 | |
| SCHEMBL20056514 | 0.85 | HSD17B1 (0.69) | HSD17B1HSD17B2ESR2HSD17B14 | |
| SCHEMBL28903928 | 0.85 | HSD17B1 (0.69) | HSD17B1HSD17B2ERN1ESR2HSD17B14 | |
| SCHEMBL20056469 | 0.83 | HSD17B1 (0.59) | HSD17B1HSD17B2ERN1ESR2HSD17B14 | |
| SCHEMBL19608277 | 0.83 | HSD17B1 (0.59) | HSD17B1HSD17B2ERN1ESR2HSD17B14 | |
| SCHEMBL12182355 | 0.82 | ERN1 (0.56) | HSD17B1HSD17B2ERN1PARP1CSF1R | |
| SCHEMBL31422694 | 0.82 | PARP1 (0.64) | ERN1PARP1DHODH | |
| SCHEMBL2431097 | 0.82 | PARP1 (0.64) | ERN1PARP1DHODH | |
| SCHEMBL3727219 | 0.81 | DHODH (0.71) | ERN1PARP1CSF1RFLT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |